phenobarbital will lower the level or effect of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Sturdy or average CYP3A4 inducers may enhance price of diazepam elimination; as a result, efficacy of diazepam could possibly be lowered.Barbiturates are respiratory depressants, and the diploma of respirato